SCHEMBL28248779

SCHEMBL28248779

Cc1c(C)c(C(=O)OO)c(O)c(O)c1C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 6/20 0.41
LDHB P07195 6/20 0.41
PSMG3 Q9BT73 1/20 0.39
DPP4 P27487 1/20 0.34
ALDH1A1 P00352 3/20 0.34
CYP3A4 P08684 5/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
MAPT P10636 3/20 0.33
TDP1 Q9NUW8 2/20 0.33
HPGD P15428 2/20 0.33
KDM4E B2RXH2 1/20 0.33
CASP1 P29466 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10404342 0.83 LDHA (0.52) LDHALDHBPSMG3DPP4ALDH1A1
SCHEMBL10142193 0.78 POLB (0.32) ALDH1A1MEN1KMT2AMAPTHPGD
SCHEMBL28345936 0.77 GLRA3 (0.34) LDHALDHBDPP4CA12CA1
SCHEMBL5590144 0.77 LDHA (0.57) LDHALDHBPSMG3DPP4ALDH1A1
SCHEMBL14090615 0.76 KMT2A (0.33) ALDH1A1MEN1KMT2AHPGDKDM4E
SCHEMBL5587007 0.76 LDHA (0.42) LDHALDHBDPP4CYP3A4MEN1
SCHEMBL1536209 0.75 ESR1 (0.30)
SCHEMBL19193900 0.74 LDHA (0.54) LDHALDHBDPP4ALDH1A1CYP3A4
SCHEMBL8830267 0.74 LDHA (0.48) LDHALDHBPSMG3DPP4ALDH1A1
SCHEMBL2946082 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103923128-B Polyoxometallate-organic chain-silsesquioxane hybrid compounds and preparation method 南开大学 2018-10-26 CN disclosed