Phenylacetic Acid

Phenylacetic Acid

SCHEMBL28249397

COc1ccc(COC=O)cc1.O=C(O)Cc1ccccc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.54
POLB P06746 1/20 0.54
NPC1 O15118 2/20 0.52
ALDH1A1 P00352 4/20 0.50
RAB9A P51151 2/20 0.50
MAPT P10636 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
PTGS1 P23219 1/20 0.50
AKR1C3 P42330 1/20 0.50
AKR1C2 P52895 1/20 0.50
USP2 O75604 1/20 0.50
TP53 P04637 1/20 0.50
PLAU P00749 1/20 0.50
ELANE P08246 1/20 0.50
HTT P42858 1/20 0.50
ALOX5 P09917 1/20 0.49
CTBP2 P56545 1/20 0.49
AKR1B1 P15121 1/20 0.49
CNR2 P34972 1/20 0.48
LTA4H P09960 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylacetic Acid SCHEMBL30136468 0.88 AKR1B1 (0.63) ALDH1A1PTGS1HTTCTBP2AKR1B1
SCHEMBL12384217 0.84 CA2 (0.57) KDM4EPOLBALDH1A1MAPTPTGS1
SCHEMBL6342 0.83 IDO1 (0.55) POLBNPC1ALDH1A1RAB9ASMN1; SMN2
Iodide SCHEMBL9356671 0.81 IDO1 (0.53) POLBNPC1ALDH1A1RAB9ASMN1; SMN2
SCHEMBL28552476 0.81 IDO1 (0.53) POLBNPC1ALDH1A1RAB9ASMN1; SMN2
SCHEMBL28560899 0.81 IDO1 (0.53) POLBNPC1ALDH1A1RAB9ASMN1; SMN2
SCHEMBL240822 0.81 KDM4E (0.74) KDM4EPOLBNPC1ALDH1A1RAB9A
Hydrochloric Acid SCHEMBL2022863 0.79 KDM4E (0.72) KDM4EPOLBNPC1ALDH1A1RAB9A
Hydrogen Sulfide SCHEMBL29062416 0.79 KDM4E (0.72) KDM4EPOLBNPC1ALDH1A1RAB9A
SCHEMBL27952524 0.79 KDM4E (0.72) KDM4EPOLBNPC1ALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108601958-A Pro-perfume compositions 爱客多有限公司 2018-09-28 CN disclosed