Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 10/20 | 0.51 |
| ▸ | DRD2 | P14416 | 7/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CCR2 | P41597 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2241423 | 0.86 | KMT2A (0.63) | DRD4DRD2MCHR1KMT2AKCNA3 | |
| SCHEMBL178929 | 0.86 | KMT2A (0.63) | DRD4DRD2MCHR1KMT2AKCNA3 | |
| SCHEMBL2241424 | 0.86 | KMT2A (0.63) | DRD4DRD2MCHR1KMT2AKCNA3 | |
| SCHEMBL1412221 | 0.82 | KMT2A (0.58) | DRD4DRD2MCHR1KMT2AKCNA3 | |
| SCHEMBL1412219 | 0.82 | KMT2A (0.58) | DRD4DRD2MCHR1KMT2AKCNA3 | |
| SCHEMBL17610296 | 0.81 | KMT2A (0.53) | DRD4DRD2MCHR1KMT2AKCNA3 | |
| SCHEMBL1412348 | 0.81 | KMT2A (0.56) | DRD4DRD2MCHR1KMT2AKCNA3 | |
| SCHEMBL5449145 | 0.81 | CCR2 (0.60) | DRD4DRD2MCHR1KMT2AL3MBTL1 | |
| SCHEMBL5449143 | 0.81 | CCR2 (0.60) | DRD4DRD2MCHR1KMT2AL3MBTL1 | |
| SCHEMBL17269909 | 0.80 | DRD2 (0.64) | DRD4DRD2MCHR1KMT2AKCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602823-A | As deubiquitinating enzymes（DUB）The spiral shell of inhibitor-condensation pyrrolidin derivatives | 特殊治疗有限公司 | 2018-09-28 | — | — | CN | disclosed |