Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 7/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | TACR3 | P29371 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | C5 | P01031 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27669534 | 0.85 | DHODH (0.61) | DHODHLMNAPDE10APOLBTSHR | |
| SCHEMBL8267472 | 0.85 | LMNA (0.82) | DHODHLMNAPDE10APOLBTSHR | |
| SCHEMBL28250066 | 0.82 | PDE10A (0.60) | DHODHLMNAPDE10APOLBTSHR | |
| SCHEMBL14492079 | 0.82 | PDE10A (0.68) | DHODHLMNAPDE10APOLBTSHR | |
| SCHEMBL1581252 | 0.82 | DHODH (0.65) | DHODHLMNAPDE10APOLBTSHR | |
| SCHEMBL6957665 | 0.82 | DHODH (0.65) | DHODHLMNAPDE10APOLBTSHR | |
| SCHEMBL4245187 | 0.82 | DHODH (0.65) | DHODHLMNAPDE10APOLBTSHR | |
| SCHEMBL4760325 | 0.82 | CYP2D6 (0.63) | DHODHLMNAPDE10APOLBTSHR | |
| SCHEMBL4601922 | 0.81 | DHODH (0.56) | DHODHLMNAPDE10APOLBTSHR | |
| SCHEMBL4601611 | 0.80 | DHODH (0.55) | DHODHLMNAPDE10APOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108752273-A | A kind of preparation method of Cinchonic Acid's derivative of 3- straight chained alkyls carboxyl substitution | 湖北欣瑞康医药科技有限公司 | 2018-11-06 | — | — | CN | disclosed |