Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 7/20 | 0.65 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | TACR3 | P29371 | 4/20 | 0.48 |
| ▸ | TACR2 | P21452 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1581252 | 0.84 | DHODH (0.65) | DHODHPDE10ALMNATSHRPOLB | |
| SCHEMBL8267472 | 0.84 | LMNA (0.82) | DHODHPDE10ALMNATSHRPOLB | |
| SCHEMBL4245187 | 0.84 | DHODH (0.65) | DHODHPDE10ALMNATSHRPOLB | |
| SCHEMBL14492079 | 0.84 | PDE10A (0.68) | DHODHPDE10ALMNATSHRPOLB | |
| SCHEMBL28250898 | 0.82 | LMNA (0.73) | DHODHPDE10ALMNATSHRPOLB | |
| SCHEMBL3908668 | 0.82 | DHODH (0.71) | DHODHPDE10ALMNATSHRPOLB | |
| SCHEMBL27669534 | 0.82 | DHODH (0.61) | DHODHPDE10ALMNATSHRPOLB | |
| SCHEMBL28250067 | 0.82 | DHODH (0.61) | DHODHPDE10ALMNATSHRPOLB | |
| SCHEMBL4665929 | 0.81 | TACR3 (0.64) | DHODHPDE10ALMNATSHRPOLB | |
| SCHEMBL4234917 | 0.81 | DHODH (0.60) | DHODHPDE10ALMNATSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337253-A1 | NOVEL COMPOUNDS | GlaxoSmithKline S.p.A. (IT) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002043734-A1 | NOVEL COMPOUNDS | GLAXOSMITHKLINE SPA (IT) | 2002-06-06 | — | — | WO | disclosed |