Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | GALR2 | O43603 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | CCR6 | P51684 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3514702 | 0.82 | TSHR (0.56) | ALDH1A1LMNATSHRKMT2AKDM4E | |
| SCHEMBL27006674 | 0.80 | TSHR (0.50) | ALDH1A1SMN1; SMN2LMNAHPGDGAA | |
| SCHEMBL5743569 | 0.77 | TSHR (0.50) | ALDH1A1LMNAHPGDGAATSHR | |
| SCHEMBL1523174 | 0.77 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2POLBLMNAGALR2 | |
| SCHEMBL8549795 | 0.77 | DTYMK (0.47) | ALDH1A1POLBLMNAGAATSHR | |
| SCHEMBL3114745 | 0.75 | KMT2A (0.42) | ALDH1A1SMN1; SMN2LMNAGAAKMT2A | |
| SCHEMBL148384 | 0.75 | MAPT (0.56) | ALDH1A1SMN1; SMN2POLBLMNAGALR2 | |
| SCHEMBL7017758 | 0.74 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2POLBLMNAGALR2 | |
| SCHEMBL13221968 | 0.74 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2LMNAGAAKMT2A | |
| SCHEMBL14114749 | 0.74 | SMN1; SMN2 (0.61) | ALDH1A1SMN1; SMN2POLBLMNAGALR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108770356-A | The tricyclic compounds and its preparation of bromodomain protein inhibitor, pharmaceutical composition and purposes | 正大天晴药业集团股份有限公司 | 2018-11-06 | — | — | CN | disclosed |