Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.66 |
| ▸ | PDE4A | P27815 | 3/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.50 |
| ▸ | PDE5A | O76074 | 2/20 | 0.50 |
| ▸ | PDE1A | P54750 | 2/20 | 0.50 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.50 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.47 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.46 |
| ▸ | AHCY | P23526 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23771392 | 0.81 | YTHDC1 (0.66) | YTHDC1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28251685 | 0.81 | ADORA3 (0.49) | YTHDC1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL763699 | 0.79 | YTHDC1 (1.00) | YTHDC1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL18548917 | 0.79 | YTHDC1 (0.62) | YTHDC1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28004897 | 0.78 | YTHDC1 (0.41) | YTHDC1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8970970 | 0.78 | YTHDC1 (0.66) | YTHDC1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28251676 | 0.78 | YTHDC1 (0.66) | YTHDC1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20041716 | 0.78 | YTHDC1 (0.66) | YTHDC1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28252117 | 0.78 | YTHDC1 (0.66) | YTHDC1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6272991 | 0.76 | YTHDC1 (0.64) | YTHDC1PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108703970-A | Compound for activating AMPK and application thereof | 华安医学股份有限公司 | 2018-10-26 | — | — | CN | disclosed |