Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31214681 | 0.89 | GHSR (0.41) | GAANFKB1NFKB2RELAMEN1 | |
| SCHEMBL7934965 | 0.85 | GAA (0.38) | GAANFKB1NFKB2RELAMEN1 | |
| SCHEMBL1953820 | 0.83 | GHSR (0.39) | GAANFKB1NFKB2RELAMEN1 | |
| SCHEMBL142219 | 0.82 | MEN1 (0.39) | GAANFKB1NFKB2RELAMEN1 | |
| SCHEMBL1425219 | 0.81 | GHSR (0.53) | GHSR | |
| SCHEMBL29707280 | 0.81 | GHSR (0.53) | GHSR | |
| SCHEMBL5404964 | 0.81 | GHSR (0.47) | GHSRCA1CA7 | |
| SCHEMBL16112133 | 0.80 | GHSR (0.37) | GAANFKB1NFKB2RELAMEN1 | |
| SCHEMBL23274329 | 0.79 | GAA (0.44) | GAANFKB1NFKB2RELAMEN1 | |
| SCHEMBL76966 | 0.79 | BTK (0.38) | GAAMEN1KMT2AGHSRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024157953-A1 | SUBSTITUTED BENZENE COMPOUND | 第一三共株式会社 | 2024-08-02 | — | — | WO | disclosed |
| CN-108794422-B | Heterocyclic compounds as PD-L1 inhibitors | 南京圣和药业股份有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-108794422-A | Heterocycle compound as PD-L1 inhibitor | 南京圣和药业股份有限公司 | 2018-11-13 | — | — | CN | disclosed |