SCHEMBL76966

SCHEMBL76966

CC(C)(C)OC(=O)NC1(C(=O)O)CCCC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BTK Q06187 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
MAPK1 P28482 1/20 0.37
FAAH O00519 4/20 0.36
GHSR Q92847 1/20 0.34
GAA P10253 2/20 0.34
ALDH1A1 P00352 1/20 0.34
CTSL P07711 1/20 0.34
APLNR P35414 1/20 0.33
EPHX1 P07099 1/20 0.33
FABP4 P15090 1/20 0.33
FABP5 Q01469 1/20 0.33
P2RX7 Q99572 1/20 0.33
PSEN1 P49768 1/20 0.33
PSEN2 P49810 1/20 0.33
APH1B Q8WW43 1/20 0.33
NCSTN Q92542 1/20 0.33
APH1A Q96BI3 1/20 0.33
PSENEN Q9NZ42 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL550992 0.98 FAAH (0.39) BTKMEN1KMT2AMAPK1FAAH
SCHEMBL1012064 0.98 FAAH (0.39) BTKMEN1KMT2AMAPK1FAAH
SCHEMBL496169 0.98 FAAH (0.39) BTKMEN1KMT2AMAPK1FAAH
SCHEMBL8980908 0.98 FAAH (0.39) BTKMEN1KMT2AMAPK1FAAH
SCHEMBL8981350 0.98 FAAH (0.39) BTKMEN1KMT2AMAPK1FAAH
SCHEMBL202837 0.96 BTK (0.38) BTKMEN1KMT2AMAPK1FAAH
SCHEMBL142219 0.92 MEN1 (0.39) BTKMEN1KMT2AMAPK1GHSR
SCHEMBL2789711 0.86 GHSR (0.37) BTKMEN1KMT2AMAPK1FAAH
SCHEMBL18482795 0.86 GAA (0.36) BTKMEN1KMT2AMAPK1GHSR
SCHEMBL2085827 0.86 CXCR5 (0.40) BTKMEN1KMT2AMAPK1GHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 543 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4687951-A1 P450-BM3 VARIANTS WITH IMPROVED ACTIVITY Codexis, Inc. (US) 2026-02-11 EP claimed
WO-2024196434-A1 P450-BM3 VARIANTS WITH IMPROVED ACTIVITY CODEXIS, INC. (US) 2024-09-26 WO claimed
US-20240318152-A1 P450-BM3 VARIANTS WITH IMPROVED ACTIVITY CODEXIS, INC. 2024-09-26 US claimed
CN-112876507-A Trisubstituted olefin tertiary phosphine compound and preparation method thereof 湖北大学 2021-06-01 CN claimed
WO-2026102082-A1 ALKYLPHENYL SUBSTITUTED COMPOUNDS, COMPOSITIONS AND METHODS OF USE DEEP APPLE THERAPEUTICS, INC. (US) 2026-05-15 WO disclosed
EP-4702033-A1 DESMURAMYLPEPTIDE DIACIDS AS NOD2 AGONISTS AND USE THEREOF Imhotex Limited (GB) 2026-03-04 EP disclosed
EP-4687951-A1 P450-BM3 VARIANTS WITH IMPROVED ACTIVITY Codexis, Inc. (US) 2026-02-11 EP disclosed
EP-4687951-A1 P450-BM3 VARIANTS WITH IMPROVED ACTIVITY Codexis, Inc. (US) 2026-02-11 EP disclosed
US-12527779-B2 Prostaglandin E2 (PGE2) EP4 receptor antagonists DOMAIN THERAPEUTICS (FR) 2026-01-20 US disclosed
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PEPTIDREAM INC (JP) 2026-01-15 US disclosed
US-12485109-B2 Pyrrolo 12.3-dipyrimidine compounds and analogues thereof BIOCRYST PHARMACEUTICALS, INC. (US) 2025-12-02 US disclosed
CN-120813367-A P450-BM3 variants with improved activity 科德克希思公司 2025-10-17 CN disclosed
US-5270331-A Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamides PFIZER, INC. (US) 1993-12-14 US disclosed
EP-0504168-A4 SYNTHETIC CALCITONIN PEPTIDES 1993-09-22 EP disclosed
US-5175146-A Improved potency; storage stability; nonhydrolyzing; osteoporosis; Paget's disease; hypocalcemic VICAL, INC. (US) 1992-12-29 US disclosed
US-5162336-A Disorders of gastrointestinal, central nervous and appetite regulatory systems RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1992-11-10 US disclosed
EP-0504168-A1 SYNTHETIC CALCITONIN PEPTIDES VICAL, INC. (US) 1992-09-23 EP disclosed
EP-0491943-A1 TETRAHYDROPYRIDOINDOLES AS CHOLECYSTOKININ AND GASTRIN ANTAGONISTS RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) 1992-07-01 EP disclosed
WO-1992000295-A1 TETRAHYDROPYRIDOINDOLES AS CHOLECYSTOKININ AND GASTRIN ANTAGONISTS RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) 1992-01-09 WO disclosed
WO-1991007978-A1 SYNTHETIC CALCITONIN PEPTIDES VICAL, INC. (US) 1991-06-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12527779-B2 Prostaglandin E2 (PGE2) EP4 receptor antagonists PTGER1, PTGER4, PTGER3 BTK 3996/4885MEN1 3795/4885KMT2A 3563/4885
US-12485109-B2 Pyrrolo 12.3-dipyrimidine compounds and analogues thereof C5, DPYD, C9 BTK 382/4885MEN1 1464/4885KMT2A 4273/4885
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF NSUN3, BCAT1, SLC43A1 BTK 2244/4885MEN1 4664/4885KMT2A 1052/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.