Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 6/20 | 0.53 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15271213 | 0.79 | FBP1 (0.58) | FBP1PRMT1TDP1ALDH1A1TSHR | |
| SCHEMBL629456 | 0.79 | FBP1 (0.58) | FBP1PRMT1TDP1ALDH1A1TSHR | |
| SCHEMBL3651740 | 0.78 | FBP1 (0.56) | FBP1PRMT1MEN1KMT2AALDH1A1 | |
| SCHEMBL30861408 | 0.75 | FBP1 (0.53) | FBP1PRMT1CYP1A2POLBALDH1A1 | |
| SCHEMBL9422615 | 0.72 | FBP1 (0.64) | FBP1PRMT1ALDH1A1TSHRAKR1C3 | |
| SCHEMBL9328703 | 0.72 | FBP1 (0.64) | FBP1PRMT1ALDH1A1TSHRAKR1C3 | |
| SCHEMBL12386158 | 0.72 | FBP1 (0.64) | FBP1PRMT1ALDH1A1TSHRAKR1C3 | |
| SCHEMBL632453 | 0.69 | FBP1 (1.00) | FBP1PRMT1ALDH1A1TSHRAKR1C3 | |
| SCHEMBL11285723 | 0.69 | FBP1 (0.60) | FBP1PRMT1ALDH1A1TSHRAKR1C3 | |
| SCHEMBL21631225 | 0.69 | FBP1 (0.60) | FBP1PRMT1ALDH1A1TSHRAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108822135-A | A kind of synthetic method of the cyclosubstituted thieno of azepine [3,2-d] thiazole and its derivative | 湘潭大学 | 2018-11-16 | — | — | CN | claimed |
| CN-108822135-A | A kind of synthetic method of the cyclosubstituted thieno of azepine [3,2-d] thiazole and its derivative | 湘潭大学 | 2018-11-16 | — | — | CN | disclosed |