Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 12/20 | 1.00 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL632451 | 1.00 | FBP1 (1.00) | FBP1PRMT1ALDH1A1TSHRAKR1C3 | |
| SCHEMBL632452 | 1.00 | FBP1 (1.00) | FBP1PRMT1ALDH1A1TSHRAKR1C3 | |
| SCHEMBL28488527 | 0.80 | FBP1 (0.70) | FBP1ALDH1A1 | |
| SCHEMBL28485590 | 0.80 | FBP1 (0.70) | FBP1ALDH1A1 | |
| SCHEMBL13983962 | 0.80 | FBP1 (0.70) | FBP1ALDH1A1 | |
| SCHEMBL630964 | 0.80 | FBP1 (1.00) | FBP1ALDH1A1AKR1C3 | |
| SCHEMBL630963 | 0.80 | FBP1 (1.00) | FBP1ALDH1A1AKR1C3 | |
| SCHEMBL525207 | 0.80 | FBP1 (1.00) | FBP1ALDH1A1AKR1C3 | |
| SCHEMBL30295762 | 0.80 | FBP1 (1.00) | FBP1ALDH1A1AKR1C3 | |
| SCHEMBL6912556 | 0.79 | FBP1 (0.65) | FBP1PRMT1AKR1C3AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106117113-A | Polysubstituted carbazole, derivant and synthetic method thereof | 湘潭大学 | 2016-11-16 | — | — | CN | claimed |
| CN-103848830-B | A kind of simple and easy method of synthesis imidazo [1,2-α] pyridine derivate | 淮阴师范学院 | 2016-08-03 | — | — | CN | claimed |
| CN-105040398-A | Improved cashmere oxidation bleaching method | NINGXIA ZHONGYIN CASHMERE CO LTD | 2015-11-11 | — | — | CN | claimed |
| CN-106117113-A | Polysubstituted carbazole, derivant and synthetic method thereof | 湘潭大学 | 2016-11-16 | — | — | CN | disclosed |
| CN-103848830-B | A kind of simple and easy method of synthesis imidazo [1,2-α] pyridine derivate | 淮阴师范学院 | 2016-08-03 | — | — | CN | disclosed |
| CN-104610003-B | A kind of method of high-efficient carrier catalyst asymmetry catalysis Michael addition | 台州学院 | 2016-07-06 | — | — | CN | disclosed |
| EP-2419094-B1 | Compounds for the treatment of mitochondrial diseases | CENTRE NAT RECH SCIENT (FR) | 2016-06-08 | — | — | EP | disclosed |
| US-9315482-B2 | Derivatives useful as antiviral agents | INSTITUT PASTEUR (FR) | 2016-04-19 | — | — | US | disclosed |
| CN-105294591-A | High-stereo and highly-enantioselective oxazolinedione compound, preparation method and application thereof | UNIV HENAN | 2016-02-03 | — | — | CN | disclosed |
| CN-105040398-A | Improved cashmere oxidation bleaching method | NINGXIA ZHONGYIN CASHMERE CO LTD | 2015-11-11 | — | — | CN | disclosed |
| CN-104945376-A | synthesizing method for 3-aroyl indole compound | UNIV ANHUI SCI & TECHNOLOGY | 2015-09-30 | — | — | CN | disclosed |
| CN-1950337-A | (4, 5,6, 7-tetrahydro-1-H-indol-7-yl) acetic acid derivatives for the treatment of Alzheimer's disease | MERCK SHARP & DOHME (GB) | 2007-04-18 | — | — | CN | disclosed |
| EP-1768986-A2 | FURANOPYRIMIDINES | Amgen Inc. (US) | 2007-04-04 | — | — | EP | disclosed |
| US-20060040961-A1 | Furanopyrimidines | AMGEN INC. | 2006-02-23 | — | — | US | disclosed |
| WO-2006004658-A2 | FURANOPYRIMIDINES | AMGEN INC. (US) | 2006-01-12 | — | — | WO | disclosed |
| CN-1026206-C | Arylpyrrole insecticidal acaricidal and nematicidal agents and method for preparation thereof | AMERICAN CYANAMID CO (US) | 1994-10-19 | — | — | CN | disclosed |
| CN-1039807-A | Desinsection, kill mite, nematocides aryl-pyrrolidine and preparation method thereof | AMERICAN CYANAMID CO (US) | 1990-02-21 | — | — | CN | disclosed |
| US-4835312-A | Production process of N-substituted amide compounds | MITSUI CHEMICALS, INCORPORATED (JP) | 1989-05-30 | — | — | US | disclosed |
| US-4119646-A | Hexahydrobenzofuranone compounds | MOBIL OIL CORPORATION (US) | 1978-10-10 | — | — | US | disclosed |
| US-4011239-A | MANGANESE, VANADIUM, CERIUM | MOBIL OIL CORPORATION (US) | 1977-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060040961-A1 | Furanopyrimidines | TYMS, IDO1, NFATC1 | FBP1 161/4885PRMT1 1302/4885ALDH1A1 159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.