Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7032529 | 0.75 | KCNJ1 (0.51) | KCNJ1KCNH2MAPTSMN1; SMN2ACHE | |
| SCHEMBL5517957 | 0.75 | MAPT (0.50) | KCNJ1KCNH2MAPTSMN1; SMN2DRD4 | |
| SCHEMBL18787069 | 0.74 | ACHE (0.52) | KCNJ1KCNH2MAPTSMN1; SMN2DRD4 | |
| SCHEMBL31298890 | 0.74 | ACHE (0.52) | KCNJ1KCNH2MAPTSMN1; SMN2ACHE | |
| SCHEMBL2616910 | 0.74 | KCNJ1 (0.45) | KCNJ1KCNH2MAPTSMN1; SMN2DRD4 | |
| SCHEMBL13007729 | 0.74 | ACHE (0.44) | KCNJ1KCNH2MAPTSMN1; SMN2ACHE | |
| SCHEMBL190557 | 0.74 | ACHE (0.48) | KCNJ1KCNH2MAPTSMN1; SMN2ACHE | |
| SCHEMBL24661328 | 0.72 | ALDH1A1 (0.49) | KCNJ1KCNH2MAPTSMN1; SMN2MEN1 | |
| SCHEMBL9143535 | 0.70 | SIRT2 (0.46) | KCNJ1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL447107 | 0.70 | ACHE (0.50) | KCNJ1KCNH2MAPTSMN1; SMN2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108727367-A | Benzoxazinones containing pyridopyrimidine dione and its preparation method and application and herbicidal composition | 山东先达农化股份有限公司 | 2018-11-02 | — | — | CN | disclosed |