⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alanine SCHEMBL28417641 | 0.89 | SLC7A5 (0.40) | — | |
| Beta-Alanine SCHEMBL28417640 | 0.82 | GABRP (0.40) | — | |
| SCHEMBL442847 | 0.79 | — | — | |
| SCHEMBL740307 | 0.79 | — | — | |
| SCHEMBL7306493 | 0.75 | — | — | |
| SCHEMBL497756 | 0.75 | CYP1A2 (0.43) | — | |
| SCHEMBL7613000 | 0.75 | CYP1A2 (0.43) | — | |
| SCHEMBL3059067 | 0.75 | — | — | |
| SCHEMBL1237678 | 0.75 | — | — | |
| SCHEMBL681236 | 0.75 | CYP1A2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111511383-A | Multifunctional immune cell therapy | 阿奇利克斯股份有限公司 | 2020-08-07 | — | — | CN | disclosed |
| CN-111315398-A | Compositions and methods of use of interleukin-10 in combination with an immune checkpoint pathway inhibitor | 阿尔莫生物科技股份有限公司 | 2020-06-19 | — | — | CN | disclosed |
| CN-111247163-A | Screening assays, modulators and modulation of activation of Receptor for Advanced Glycation Endproducts (RAGE) | 莫纳施大学 | 2020-06-05 | — | — | CN | disclosed |
| CN-111107870-A | Modified membrane serine protease 1(MTSP-1) polypeptides and methods of use thereof | 催化剂生物科学公司 | 2020-05-05 | — | — | CN | disclosed |
| CN-103420950-B | Amino acid base biodegradable 2-expoxy compound and preparation method thereof | SHANGHAI LANGYI FUNCTIONAL MATERIALS CO LTD | 2015-02-18 | — | — | CN | disclosed |
| CN-103420950-A | Amino acid base biodegradable 2-expoxy compound and preparation method thereof | SHANGHAI LANGYI FUNCTIONAL MATERIALS CO LTD | 2013-12-04 | — | — | CN | disclosed |
| EP-2242765-A1 | SHORT FATTY ACID TAIL POLYMYXIN DERIVATIVES AND USES THEREOF | Northern Antibiotics Oy (FI) | 2010-10-27 | — | — | EP | disclosed |
| WO-2009098357-A1 | SHORT FATTY ACID TAIL POLYMYXIN DERIVATIVES AND USES THEREOF | NORTHERN ANTIBIOTICS OY (FI) | 2009-08-13 | — | — | WO | disclosed |
| EP-1261611-A2 | INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE | Bristol-Myers Squibb Pharma Company (US) | 2002-12-04 | — | — | EP | disclosed |
| EP-1252178-A1 | ALPHA-KETOAMIDE INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE | Bristol-Myers Squibb Pharma Company (US) | 2002-10-30 | — | — | EP | disclosed |
| WO-2001064678-A2 | INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-09-07 | — | — | WO | disclosed |
| WO-2001040262-A1 | ALPHA-KETOAMIDE INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-06-07 | — | — | WO | disclosed |
| US-5256806-A | Intermediates for the preparation of optically active cyclobutane nucleoside | E. R. SQUIBB & SONS, INC. (US) | 1993-10-26 | — | — | US | disclosed |