Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ARG1 | P05089 | 1/20 | 0.33 |
| ▸ | ARG2 | P78540 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.31 |
| ▸ | GABRP | O00591 | 3/20 | 0.31 |
| ▸ | GABRD | O14764 | 3/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2825358 | 0.89 | — | — | |
| Alanine SCHEMBL2516252 | 0.79 | ALDH1A1 (0.44) | SLC7A5CYP1A2CYP2D6ALDH1A1MAPT | |
| Alanine SCHEMBL27704692 | 0.79 | ALDH1A1 (0.44) | SLC7A5CYP1A2CYP2D6ALDH1A1MAPT | |
| Alanine SCHEMBL15602815 | 0.78 | — | — | |
| Alanine SCHEMBL15602693 | 0.78 | — | — | |
| Alanine SCHEMBL2784274 | 0.78 | — | — | |
| Alanine SCHEMBL14764702 | 0.78 | SLC7A5 (0.59) | SLC7A5ALDH1A1MAPTPTGS1TP53 | |
| Alanine SCHEMBL1332110 | 0.78 | — | — | |
| D-Alanine SCHEMBL614024 | 0.78 | SLC7A5 (0.59) | SLC7A5ALDH1A1MAPTPTGS1TP53 | |
| Alanine SCHEMBL452350 | 0.78 | SLC7A5 (0.59) | SLC7A5ALDH1A1MAPTPTGS1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111247163-A | Screening assays, modulators and modulation of activation of Receptor for Advanced Glycation Endproducts (RAGE) | 莫纳施大学 | 2020-06-05 | — | — | CN | disclosed |