Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2825493 | 0.88 | HSP90AA1 (0.34) | FFAR1GRM5PPARGPPARDPPARA | |
| SCHEMBL2070933 | 0.82 | PPARD (0.50) | PPARGPPARDPPARAPTGDR2 | |
| SCHEMBL2068916 | 0.81 | PPARD (0.42) | PPARGPPARDPPARAPTGDR2 | |
| SCHEMBL2827431 | 0.79 | PPARG (0.40) | FFAR1GRM5PPARGPPARDPPARA | |
| SCHEMBL12646847 | 0.76 | PPARD (0.45) | PPARGPPARDPPARAPTGDR2 | |
| SCHEMBL2820978 | 0.68 | GRM5 (0.44) | GRM5 | |
| SCHEMBL2827433 | 0.67 | PPARG (0.38) | FFAR1GRM5PPARGPPARDPPARA | |
| SCHEMBL27741997 | 0.63 | ALDH1A1 (0.46) | HSP90AA1HSP90AB1 | |
| SCHEMBL20945362 | 0.63 | KDM4E (0.43) | FFAR1 | |
| SCHEMBL29791106 | 0.63 | KDM4E (0.43) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745003-B1 | NOVEL COMPOUNDS, THEIR PREPARATION AND USE | HIGH POINT PHARMACEUTICALS LLC (US) | 2010-10-27 | — | — | EP | claimed |