Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.37 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 3/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2827431 | 0.88 | PPARG (0.40) | PPARGPPARDPPARAEGLN1EGLN3 | |
| SCHEMBL2822197 | 0.85 | GRM5 (0.43) | PPARGPPARDPPARAESR2FFAR1 | |
| SCHEMBL2069047 | 0.80 | PPARD (0.59) | PPARGPPARDPPARA | |
| SCHEMBL2825493 | 0.79 | HSP90AA1 (0.34) | PPARGPPARDPPARAESR1ESR2 | |
| SCHEMBL2068571 | 0.78 | PPARD (0.50) | PPARGPPARDPPARAEGLN1FFAR1 | |
| SCHEMBL2823409 | 0.77 | PPARD (0.42) | PPARDEGLN1EGLN3ACACB | |
| SCHEMBL12646902 | 0.73 | PPARD (0.53) | PPARGPPARDPPARA | |
| SCHEMBL2822186 | 0.72 | PPARD (0.43) | PPARGPPARDPPARAEGLN1ESR1 | |
| SCHEMBL2822191 | 0.71 | GRM5 (0.43) | PPARGPPARDPPARAFFAR1GRM5 | |
| SCHEMBL5176957 | 0.71 | ACACB (0.40) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745003-B1 | NOVEL COMPOUNDS, THEIR PREPARATION AND USE | HIGH POINT PHARMACEUTICALS LLC (US) | 2010-10-27 | — | — | EP | claimed |