Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | HTR5A | P47898 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27307 | 0.81 | AHR (0.47) | STAT3STAT1KIF11AHRKDM4E | |
| SCHEMBL13504831 | 0.80 | STAT3 (0.42) | STAT3STAT1KDM4EMEN1GABRP | |
| SCHEMBL2749736 | 0.79 | AHR (0.45) | STAT3STAT1KIF11AHRKDM4E | |
| SCHEMBL6417535 | 0.79 | STAT3 (0.39) | STAT3STAT1KDM4EGABRPGABRD | |
| SCHEMBL310134 | 0.78 | STAT3 (0.50) | STAT3STAT1 | |
| Carbazole SCHEMBL27848555 | 0.76 | ALDH1A1 (0.52) | STAT3STAT1KIF11AHRKDM4E | |
| Triphenylene SCHEMBL28084435 | 0.75 | STAT3 (0.44) | STAT3STAT1AHRKDM4EMEN1 | |
| Carbazole SCHEMBL27824098 | 0.75 | ALDH1A1 (0.50) | STAT3STAT1KIF11AHRKDM4E | |
| Carbazole SCHEMBL28879059 | 0.75 | ALDH1A1 (0.50) | STAT3STAT1KIF11AHRKDM4E | |
| Carbamic Acid SCHEMBL6411899 | 0.74 | KDM4E (0.42) | STAT3STAT1KIF11AHRHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247447-A1 | DRUG DELIVERY SYSTEM FOR HYDROPHOBIC DRUGS | BAUSCH HEALTH COMPANIES INC. (CA) | 2010-09-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100247447-A1 | DRUG DELIVERY SYSTEM FOR HYDROPHOBIC DRUGS | LIPA, MLEC, ABCG2 | STAT3 3700/4885STAT1 4562/4885KIF11 493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.