Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 3/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.33 |
| ▸ | MPL | P40238 | 2/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13504831 | 0.89 | STAT3 (0.42) | STAT3STAT1KDM4EMAPTTP53 | |
| SCHEMBL9095058 | 0.87 | STAT3 (0.45) | STAT3STAT1KDM4EMAPTTP53 | |
| SCHEMBL351897 | 0.81 | STAT3 (0.45) | STAT3STAT1MAPTHSD17B10BRD4 | |
| SCHEMBL1597373 | 0.79 | STAT3 (0.43) | STAT3STAT1MAPTHSD17B10BRD4 | |
| SCHEMBL2825510 | 0.79 | STAT3 (0.43) | STAT3STAT1KDM4EMAPTHSD17B10 | |
| SCHEMBL1596068 | 0.78 | STAT3 (0.47) | STAT3STAT1KDM4EMAPTHSD17B10 | |
| SCHEMBL351526 | 0.77 | STAT3 (0.43) | STAT3STAT1MAPTHSD17B10BRD4 | |
| SCHEMBL2774805 | 0.77 | CYCS (0.49) | STAT3STAT1KDM4EALDH1A1HPGD | |
| SCHEMBL351525 | 0.76 | BRD4 (0.35) | STAT3STAT1KDM4EMAPTHSD17B10 | |
| SCHEMBL27307 | 0.76 | AHR (0.47) | STAT3STAT1KDM4EMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1450790-A4 | PHOTOSENSITIZING CARBAMATE DERIVATIVES | MIRAVANT PHARM INC (US) | 2005-10-26 | — | — | EP | disclosed |
| US-20040266748-A1 | Photosensitizing carbamate derivatives | MIRAVANT PHARMACEUTICALS, INC. | 2004-12-30 | — | — | US | disclosed |
| EP-1450790-A2 | PHOTOSENSITIZING CARBAMATE DERIVATIVES | Miravant Pharmaceuticals, Inc. (US) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003028628-A2 | PHOTOSENSITIZING CARBAMATE DERIVATIVES | MIRAVANT PHARMACEUTICALS, INC. (US) | 2003-04-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266748-A1 | Photosensitizing carbamate derivatives | CRY1, CASP3, CRY2 | STAT3 3053/4885STAT1 2564/4885KDM4E 238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.