Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 9/20 | 0.43 |
| ▸ | MAOB | P27338 | 5/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23856027 | 1.00 | KDM1A (0.43) | KDM1AMAOBSLC6A4CISD1SLC6A2 | |
| SCHEMBL18817699 | 1.00 | KDM1A (0.43) | KDM1AMAOBSLC6A4CISD1SLC6A2 | |
| SCHEMBL19609797 | 0.85 | SLC6A4 (0.42) | KDM1AMAOBSLC6A4CISD1SLC6A2 | |
| SCHEMBL18817746 | 0.82 | KDM1A (0.41) | KDM1AMAOBSLC6A4CISD1SLC6A2 | |
| SCHEMBL21775670 | 0.82 | KDM1A (0.41) | KDM1AMAOBSLC6A4CISD1SLC6A2 | |
| SCHEMBL18817744 | 0.82 | KDM1A (0.41) | KDM1AMAOBSLC6A4CISD1SLC6A2 | |
| SCHEMBL23867768 | 0.82 | KDM1A (0.41) | KDM1AMAOBSLC6A4CISD1SLC6A2 | |
| SCHEMBL21784349 | 0.82 | KDM1A (0.41) | KDM1AMAOBSLC6A4CISD1SLC6A2 | |
| SCHEMBL19091464 | 0.82 | KDM1A (0.41) | KDM1AMAOBSLC6A4CISD1SLC6A2 | |
| SCHEMBL22279799 | 0.78 | KDM1A (0.47) | KDM1AMAOBSLC6A4CISD1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884029-A | L SD1 inhibitors | 米拉蒂医疗股份有限公司 | 2018-11-23 | — | — | CN | disclosed |