Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.42 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 4/20 | 0.40 |
| ▸ | KDM1A | O60341 | 5/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23856027 | 0.85 | KDM1A (0.43) | SLC6A4SLC6A2MAOAKDM1AMAOB | |
| SCHEMBL28255285 | 0.85 | KDM1A (0.43) | SLC6A4SLC6A2MAOAKDM1AMAOB | |
| SCHEMBL18817699 | 0.85 | KDM1A (0.43) | SLC6A4SLC6A2MAOAKDM1AMAOB | |
| SCHEMBL19609175 | 0.81 | MAOA (0.36) | SSTR1SSTR4MAOATACR1KDM1A | |
| SCHEMBL23653316 | 0.81 | MAOA (0.33) | SSTR1SSTR4MAOATACR1KDM1A | |
| Hydrochloric Acid SCHEMBL22465821 | 0.81 | MAOA (0.36) | SSTR1SSTR4MAOATACR1KDM1A | |
| SCHEMBL25455143 | 0.80 | MGLL (0.35) | SSTR1SSTR4MAOATACR1KDM1A | |
| SCHEMBL25455147 | 0.80 | MGLL (0.35) | SSTR1SSTR4MAOATACR1KDM1A | |
| SCHEMBL21843313 | 0.80 | MGLL (0.35) | SSTR1SSTR4MAOATACR1KDM1A | |
| SCHEMBL21775670 | 0.79 | KDM1A (0.41) | SLC6A4SLC6A2SSTR1SSTR4MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017195216-A1 | CYCLOPROPYL-AMIDE COMPOUNDS AS DUAL LSD1/HDAC INHIBITORS | JUBILANT BIOSYS LIMITED (IN) | 2017-11-16 | — | — | WO | disclosed |