Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4756143 | 0.87 | MAPT (0.54) | MAPTRAB9ACA1CA2PARP15 | |
| SCHEMBL927657 | 0.86 | PARP15 (0.66) | MAPTRAB9ACA1CA2PARP15 | |
| SCHEMBL28866432 | 0.84 | L3MBTL1 (0.54) | MAPTRAB9APARP15PARP10SMN1; SMN2 | |
| SCHEMBL2614739 | 0.83 | MAPT (0.60) | MAPTRAB9ACA1CA2NPC1 | |
| SCHEMBL7311285 | 0.82 | PARP10 (0.68) | MAPTRAB9ACA1CA2PARP15 | |
| SCHEMBL30198 | 0.81 | PARP15 (0.59) | MAPTRAB9ACA1CA2PARP15 | |
| SCHEMBL240271 | 0.79 | TDP1 (0.64) | MAPTRAB9ACA1CA2PARP15 | |
| SCHEMBL12331297 | 0.79 | L3MBTL1 (0.50) | MAPTPARP15PARP10NPC1PARP2 | |
| SCHEMBL9577038 | 0.79 | PARP15 (0.57) | MAPTRAB9ACA1CA2PARP15 | |
| SCHEMBL1963756 | 0.79 | PARP15 (0.57) | MAPTRAB9ACA1CA2PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108822060-A | A kind of 3- aryl replaces oxetanes and preparation method thereof | 黄淮学院 | 2018-11-16 | — | — | CN | disclosed |