Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | EGFR | P00533 | 2/20 | 0.53 |
| ▸ | RAF1 | P04049 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | EEF2K | O00418 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6888226 | 0.87 | CES1 (0.47) | ALDH1A1CES1KDM4ELMNA | |
| SCHEMBL4202385 | 0.79 | MAPT (0.63) | MAPTALDH1A1L3MBTL1TDP1NPSR1 | |
| SCHEMBL13244107 | 0.76 | BACE1 (0.46) | MAPTALDH1A1MAPK1LMNA | |
| SCHEMBL28522247 | 0.73 | MAPT (0.57) | MAPTALDH1A1MAPK1L3MBTL1EGFR | |
| Hydrochloric Acid SCHEMBL15282882 | 0.72 | MAPT (0.55) | MAPTALDH1A1MAPK1L3MBTL1EGFR | |
| SCHEMBL2463193 | 0.69 | MAPT (1.00) | MAPTALDH1A1MAPK1L3MBTL1EGFR | |
| SCHEMBL28339971 | 0.68 | MAPT (0.54) | MAPTALDH1A1MAPK1L3MBTL1EGFR | |
| SCHEMBL3273424 | 0.68 | MAPT (0.97) | MAPTALDH1A1MAPK1L3MBTL1EGFR | |
| Isatin SCHEMBL4625841 | 0.68 | MAOA (0.69) | ALDH1A1MAOAMAOBERBB2KMT2A | |
| SCHEMBL4242823 | 0.67 | CES1 (0.60) | MAPTCES1MAOAMAOBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108912127-B | Benzo [ b, e ] azepine compound based on isatin skeleton and preparation method thereof | 青岛农业大学 | 2019-12-10 | — | — | CN | claimed |
| CN-108912127-A | A kind of benzo [b, e] azatropylidene compound and preparation method thereof based on isatin skeleton | 青岛农业大学 | 2018-11-30 | — | — | CN | claimed |
| CN-112574108-B | Preparation method of polysubstituted benzo [ b ] azepine compound | 甘肃兴荣精细化工有限公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-112574108-A | Preparation method of polysubstituted benzo [ b ] aza compound | 兰州大学 | 2021-03-30 | — | — | CN | disclosed |
| CN-108912127-B | Benzo [ b, e ] azepine compound based on isatin skeleton and preparation method thereof | 青岛农业大学 | 2019-12-10 | — | — | CN | disclosed |
| CN-108912127-B | Benzo [ b, e ] azepine compound based on isatin skeleton and preparation method thereof | 青岛农业大学 | 2019-12-10 | — | — | CN | disclosed |
| CN-108912127-A | A kind of benzo [b, e] azatropylidene compound and preparation method thereof based on isatin skeleton | 青岛农业大学 | 2018-11-30 | — | — | CN | disclosed |
| CN-108912127-A | A kind of benzo [b, e] azatropylidene compound and preparation method thereof based on isatin skeleton | 青岛农业大学 | 2018-11-30 | — | — | CN | disclosed |