Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | EGFR | P00533 | 2/20 | 0.54 |
| ▸ | RAF1 | P04049 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.54 |
| ▸ | NSD2 | O96028 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | EEF2K | O00418 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28342506 | 0.79 | ALDH1A1 (0.50) | MAPTMAPK1L3MBTL1ALDH1A1EGFR | |
| SCHEMBL28340052 | 0.76 | MAPT (0.50) | MAPTMAPK1L3MBTL1ALDH1A1EGFR | |
| SCHEMBL28339973 | 0.76 | L3MBTL1 (0.54) | MAPTMAPK1L3MBTL1ALDH1A1EGFR | |
| SCHEMBL7756746 | 0.74 | TTR (0.52) | ALDH1A1KMT2ALMNATTRCES1 | |
| SCHEMBL15206754 | 0.73 | TTR (0.50) | MAPTMAPK1ALDH1A1EGFRKMT2A | |
| SCHEMBL28074688 | 0.73 | TTR (0.50) | MAPTMAPK1ALDH1A1EGFRKMT2A | |
| SCHEMBL2290914 | 0.73 | TTR (0.50) | MAPTALDH1A1KMT2ATTRCES1 | |
| SCHEMBL21848273 | 0.73 | TTR (0.50) | ALDH1A1KMT2ATTRCES1MEN1 | |
| SCHEMBL1137933 | 0.73 | TTR (0.55) | MAPTMAPK1L3MBTL1ALDH1A1RAF1 | |
| SCHEMBL754994 | 0.73 | CES1 (0.50) | MAPTMAPK1ALDH1A1NSD2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108912127-B | Benzo [ b, e ] azepine compound based on isatin skeleton and preparation method thereof | 青岛农业大学 | 2019-12-10 | — | — | CN | disclosed |