Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29413198 | 0.94 | — | — | |
| SCHEMBL4370352 | 0.94 | — | — | |
| Formic Acid Methyl Ester SCHEMBL27958845 | 0.87 | NFE2L2 (0.43) | PLAUPDGFRBPDGFRANFE2L2NAPRT | |
| Formic Acid SCHEMBL27958614 | 0.87 | PLAU (0.44) | PLAUPDGFRBPDGFRANFE2L2NAPRT | |
| Formaldehyde SCHEMBL28298897 | 0.76 | PLAU (0.43) | PLAUPDGFRBPDGFRANFE2L2CA12 | |
| SCHEMBL13330989 | 0.76 | PDE10A (0.42) | PLAUPDGFRBPDGFRA | |
| SCHEMBL2370946 | 0.74 | CHRNB2 (0.47) | PLAUPDGFRBPDGFRANAPRTCHRNB2 | |
| SCHEMBL63365 | 0.74 | CHRNB4 (0.49) | PLAUPDGFRBPDGFRANFE2L2CA12 | |
| SCHEMBL29612256 | 0.74 | CHRNB4 (0.49) | PLAUPDGFRBPDGFRANFE2L2CA12 | |
| SCHEMBL18833817 | 0.73 | CHRNB2 (0.49) | CHRNB2CHRNA6CHRNA4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108840857-A | A kind of preparation method of quinoline | 湖南华腾制药有限公司 | 2018-11-20 | — | — | CN | disclosed |