Diphenylamine

Diphenylamine

SCHEMBL28255752

O=P(O)(O)OP(=O)(O)O.c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.55
ALDH1A1 P00352 7/20 0.52
TDP1 Q9NUW8 3/20 0.52
TSHR P16473 3/20 0.52
ALOX12 P18054 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
ALOX15 P16050 1/20 0.52
PTGS1 P23219 1/20 0.52
SLC6A2 P23975 1/20 0.52
MAPK1 P28482 1/20 0.52
PTGS2 P35354 1/20 0.52
HTR2B P41595 1/20 0.52
CASP3 P42574 1/20 0.48
SENP7 Q9BQF6 1/20 0.48
CA12 O43570 1/20 0.47
CA9 Q16790 1/20 0.47
MAPK13 O15264 1/20 0.47
MAPK12 P53778 1/20 0.47
MAPK11 Q15759 1/20 0.47
MAPK14 Q16539 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylamine SCHEMBL27245440 0.85 HSD17B10 (0.67) HSD17B10ALDH1A1TDP1TSHRALOX12
Diphenylamine SCHEMBL27245439 0.85 HSD17B10 (0.67) HSD17B10ALDH1A1TDP1TSHRALOX12
Diphenylamine SCHEMBL28255754 0.85 HSD17B10 (0.67) HSD17B10ALDH1A1TDP1TSHRALOX12
Biphenyl SCHEMBL8424826 0.78 ACP3 (0.56) HSD17B10ALDH1A1TDP1TSHRCA9
Diphenylamine SCHEMBL10938477 0.77 HSD17B10 (0.55) HSD17B10ALDH1A1TDP1TSHRALOX12
Diphenylamine SCHEMBL28222060 0.77 HSD17B10 (0.92) HSD17B10ALDH1A1TDP1TSHRALOX12
Pyrophosphoric Acid SCHEMBL28436036 0.77 FDPS (0.77) HSD17B10ALDH1A1TDP1TSHRSRC
Pyrophosphoric Acid SCHEMBL1839096 0.77 MAPT (0.39) HSD17B10ALDH1A1TDP1TSHRCA12
Pyrophosphoric Acid SCHEMBL3974840 0.76 TDP1 (0.55) HSD17B10ALDH1A1TDP1TSHRCA12
Biphenyl SCHEMBL17801640 0.76 ACP3 (0.54) HSD17B10ALDH1A1TDP1TSHRCA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108912011-A Light arrangement material 罗立克科技股份公司 2018-11-30 CN disclosed