Urea

Urea

SCHEMBL28256293

C=O.NC(N)=O.OB(O)Oc1ccccc1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 3/20 0.42
CTNNB1 P35222 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
TDP1 Q9NUW8 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
HSD17B10 Q99714 2/20 0.38
POLB P06746 1/20 0.38
CYP3A4 P08684 1/20 0.38
PARP1 P09874 1/20 0.38
MAPT P10636 1/20 0.38
TSHR P16473 1/20 0.38
CYP2C19 P33261 1/20 0.38
RECQL P46063 1/20 0.38
BLM P54132 1/20 0.38
PMP22 Q01453 1/20 0.38
ALOX15 P16050 2/20 0.38
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
USP2 O75604 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetamide SCHEMBL28100878 0.88 PARP10 (0.42) PARP10CTNNB1MEN1KMT2ATDP1
Acrylamide SCHEMBL28104682 0.86 THRB (0.41) PARP10CTNNB1MEN1KMT2ATDP1
Ethylene SCHEMBL50747 0.84 CA1 (0.43) TSHRCYP2C19RECQLALOX15CA1
SCHEMBL28102434 0.84 CA1 (0.46) TSHRRECQLALOX15CA1CA2
SCHEMBL28337059 0.84 CA1 (0.46) TSHRRECQLALOX15CA1CA2
SCHEMBL78440 0.84 CA1 (0.46) TSHRRECQLALOX15CA1CA2
Benzene SCHEMBL28134938 0.84 CA1 (0.46) TSHRRECQLALOX15CA1CA2
Phenol SCHEMBL28255142 0.83 CA1 (0.46) TDP1HSD17B10CYP3A4TSHRCYP2C19
Acetone SCHEMBL29216727 0.83 MTNR1A (0.40) L3MBTL1HSD17B10MAPTTSHRALOX15
Guanidine SCHEMBL28154633 0.83 F2 (0.41) PARP10CTNNB1KMT2ATSHRRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108950720-A A method of the modified high ortho phenolic fiber of phenyl-borate is prepared by wet spinning 中原工学院 2018-12-07 CN claimed
CN-108950720-A A method of the modified high ortho phenolic fiber of phenyl-borate is prepared by wet spinning 中原工学院 2018-12-07 CN disclosed
CN-108950873-A A kind of preparation method of the high hollow nanometer gradient activated carbon fiber film of ortho position phenyl-borate modified heat convertible phenolic aldehyde base 中原工学院 2018-12-07 CN disclosed