Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dopamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.95 |
| ▸ | MAPT | P10636 | 3/20 | 0.95 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.95 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.95 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.95 |
| ▸ | DRD2 | P14416 | 2/20 | 0.95 |
| ▸ | DRD1 | P21728 | 2/20 | 0.95 |
| ▸ | DRD4 | P21917 | 2/20 | 0.95 |
| ▸ | DRD5 | P21918 | 2/20 | 0.95 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.95 |
| ▸ | DRD3 | P35462 | 2/20 | 0.95 |
| ▸ | RECQL | P46063 | 2/20 | 0.95 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.95 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.95 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.95 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.95 |
| ▸ | APEX1 | P27695 | 2/20 | 0.95 |
| ▸ | TP53 | P04637 | 1/20 | 0.95 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.95 |
| ▸ | HTR1A | P08908 | 1/20 | 0.95 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dopamine SCHEMBL29732749 | 1.00 | KDM4E (0.95) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL29201795 | 0.98 | KDM4E (0.96) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL29362033 | 0.98 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL29375089 | 0.98 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL16685137 | 0.98 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL30379944 | 0.98 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL9166387 | 0.98 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL496657 | 0.98 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL8505 | 0.98 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A | |
| Dopamine SCHEMBL18159501 | 0.98 | KDM4E (1.00) | KDM4EMAPTMAPK1TAAR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113594427-B | MoS 2 Negative electrode material of-MoP quantum dot @ carbon composite sodium ion battery and preparation method of negative electrode material | 上海大学 | 2022-11-18 | — | — | CN | claimed |
| CN-113594427-A | MoS2Negative electrode material of-MoP quantum dot @ carbon composite sodium ion battery and preparation method of negative electrode material | 上海大学 | 2021-11-02 | — | — | CN | claimed |
| CN-108816292-A | Preparation method and application of polydopamine/nano molybdenum disulfide photocatalyst | 安徽大学 | 2018-11-16 | — | — | CN | claimed |
| CN-118099418-A | Anode composite material and preparation method and application thereof | 江苏正力新能电池技术有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-116411310-A | Fluorine doped Mo on nitrogen carbon nano sheet 2 Preparation method of C nano catalyst | 河北工业大学 | 2023-07-11 | — | — | CN | disclosed |
| CN-116411310-A | Fluorine doped Mo on nitrogen carbon nano sheet 2 Preparation method of C nano catalyst | 河北工业大学 | 2023-07-11 | — | — | CN | disclosed |
| CN-116190649-A | MoO grows on mesoporous hollow carbon sphere surface in situ 2 Nanosheet composite material | 长治学院 | 2023-05-30 | — | — | CN | disclosed |
| CN-116190649-A | MoO grows on mesoporous hollow carbon sphere surface in situ 2 Nanosheet composite material | 长治学院 | 2023-05-30 | — | — | CN | disclosed |
| CN-113594427-B | MoS 2 Negative electrode material of-MoP quantum dot @ carbon composite sodium ion battery and preparation method of negative electrode material | 上海大学 | 2022-11-18 | — | — | CN | disclosed |
| CN-113121821-B | Multistage titanium dopamine composite material and preparation method and application thereof | 西北工业大学 | 2022-06-17 | — | — | CN | disclosed |
| CN-113594427-A | MoS2Negative electrode material of-MoP quantum dot @ carbon composite sodium ion battery and preparation method of negative electrode material | 上海大学 | 2021-11-02 | — | — | CN | disclosed |
| CN-113121821-A | Multistage titanium dopamine composite material and preparation method and application thereof | 西北工业大学 | 2021-07-16 | — | — | CN | disclosed |