Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 5/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913896 | 0.84 | ALDH1A1 (0.56) | ALDH1A3CSF1RALDH1A1POLBMAPK1 | |
| Tert-Butyl Formate SCHEMBL28128153 | 0.80 | CHKA (0.52) | ALDH1A1MAPK1HPGDGAAKDM4E | |
| Tert-Butyl Formate SCHEMBL28256683 | 0.74 | TMEM97 (0.43) | — | |
| SCHEMBL7918934 | 0.73 | ALDH1A1 (0.46) | ALDH1A3CSF1RALDH1A1POLBMAPK1 | |
| Tert-Butyl Formate SCHEMBL28840470 | 0.72 | ALDH1A1 (0.47) | ALDH1A3ALDH1A1POLBMAPK1HPGD | |
| SCHEMBL10088504 | 0.70 | ALDH1A1 (0.53) | ALDH1A3CSF1RALDH1A1POLBMAPK1 | |
| SCHEMBL10088914 | 0.70 | NOTUM (0.47) | CSF1R | |
| SCHEMBL27918364 | 0.70 | ALDH1A1 (0.44) | ALDH1A3CSF1RALDH1A1MAPK1HPGD | |
| Tert-Butyl Formate SCHEMBL28127213 | 0.69 | ALDH1A1 (0.43) | ALDH1A3ALDH1A1POLBMAPK1GAA | |
| SCHEMBL5022655 | 0.69 | ALDH1A1 (0.61) | ALDH1A3CSF1RALDH1A1POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071560-A | Thienopyridine formamide as ubiquitin-specific protease inhibitor | 福马治疗股份有限公司 | 2018-12-21 | — | — | CN | disclosed |