Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | GAA | P10253 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | YWHAG | P61981 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28127213 | 0.92 | ALDH1A1 (0.43) | ALDH1A1POLBMAPTGAAMEN1 | |
| SCHEMBL15509139 | 0.86 | MAPT (0.59) | ALDH1A1POLBMAPTGAAMEN1 | |
| SCHEMBL17265653 | 0.80 | MAPT (0.54) | ALDH1A1POLBMAPTGAAMEN1 | |
| Tert-Butyl Formate SCHEMBL28332257 | 0.78 | HTR6 (0.40) | ALDH1A1MAPTGAAMEN1KMT2A | |
| Tert-Butyl Formate SCHEMBL28126522 | 0.77 | ALDH1A1 (0.61) | ALDH1A1POLBMAPTGAAMEN1 | |
| SCHEMBL6680044 | 0.76 | HTT (0.48) | ALDH1A1POLBMAPTGAAMEN1 | |
| SCHEMBL18186268 | 0.76 | MEN1 (0.46) | ALDH1A1POLBMAPTGAAMEN1 | |
| SCHEMBL24992422 | 0.75 | NR1H2 (0.52) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL6681898 | 0.74 | MAPT (0.47) | ALDH1A1POLBMAPTGAAMEN1 | |
| SCHEMBL12006141 | 0.74 | MAPT (0.61) | ALDH1A1POLBMAPTGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106470985-A | Indane and indoline derivatives as soluble guanylate cyclase activators and uses thereof | 诺华股份有限公司 | 2017-03-01 | — | — | CN | disclosed |