1,4-Dichlorobenzene

1,4-Dichlorobenzene

SCHEMBL28257308

CCC(=O)CC.Clc1ccc(Cl)cc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.56
CES2 O00748 2/20 0.48
CES1 P23141 2/20 0.48
GSK3B P49841 2/20 0.46
ALOX15 P16050 1/20 0.46
TSHR P16473 1/20 0.46
HTT P42858 1/20 0.45
ALDH1A1 P00352 3/20 0.44
LMNA P02545 2/20 0.44
KDM4E B2RXH2 2/20 0.44
CYP2A6 P11509 1/20 0.44
MAPT P10636 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
POLB P06746 1/20 0.42
GAA P10253 1/20 0.42
CTDSP1 Q9GZU7 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28273770 0.89 POLB (0.45) TDP1HTTALDH1A1MAPTPOLB
Chlorobenzene SCHEMBL27453116 0.87 TSHR (0.52) TDP1CES2CES1ALOX15TSHR
SCHEMBL28084159 0.85 POLB (0.59) HTTALDH1A1LMNAMAPTMEN1
SCHEMBL28106467 0.84 TDP1 (0.43) TDP1CES2CES1GSK3BALOX15
SCHEMBL3070923 0.84 L3MBTL1 (0.52) TDP1ALDH1A1LMNAKDM4EMAPT
1,4-Dichlorobenzene SCHEMBL27561831 0.83 FFAR3 (0.56) CES2CES1GSK3BALOX15TSHR
1,4-Dichlorobenzene SCHEMBL27864019 0.83 ALDH1A1 (0.56) TDP1CES2CES1GSK3BALOX15
1,4-Dichlorobenzene SCHEMBL27511316 0.82 ALDH1A1 (0.54) CES2CES1HTTALDH1A1LMNA
1,4-Dichlorobenzene SCHEMBL27647226 0.81 NPC1 (0.52) CES2CES1GSK3BALOX15TSHR
SCHEMBL27504119 0.80 PARP1 (0.47) TDP1TSHRHTTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108887265-A Promote the regulator of plant failure cell fast-growth 金华市景和科技有限公司 2018-11-27 CN disclosed