SCHEMBL28257533

SCHEMBL28257533

NC(=O)c1cccc(C(=O)O)c1C=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.44
ALOX15 P16050 2/20 0.44
ERN1 O75460 1/20 0.44
G6PD P11413 1/20 0.42
CASP7 P55210 1/20 0.42
CASP6 P55212 1/20 0.42
MMP2 P08253 1/20 0.42
BCAT2 O15382 1/20 0.42
KDM4E B2RXH2 4/20 0.42
HPGD P15428 3/20 0.42
MAPT P10636 2/20 0.42
TSHR P16473 2/20 0.42
HSD17B10 Q99714 2/20 0.42
LMNA P02545 1/20 0.40
F2 P00734 1/20 0.40
PRSS1 P07477 1/20 0.40
PRSS2 P07478 1/20 0.40
PRSS3 P35030 1/20 0.40
NR4A1 P22736 1/20 0.39
NR4A2 P43354 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11718261 0.89 ALDH1A1 (0.55) ALDH1A1ALOX15G6PDCASP7CASP6
Benzene SCHEMBL28172839 0.89 ALDH1A1 (0.55) ALDH1A1ALOX15G6PDCASP7CASP6
SCHEMBL15210226 0.80 ERN1 (0.44) ALDH1A1ERN1BCAT2KDM4EHPGD
SCHEMBL29951147 0.80 KDM4E (0.57) ALDH1A1ERN1G6PDCASP7CASP6
SCHEMBL27573865 0.78 ERN1 (0.47) ALDH1A1ERN1KDM4EHPGDMAPT
SCHEMBL4985110 0.78 ALDH1A1 (0.56) ALDH1A1ALOX15ERN1G6PDCASP7
SCHEMBL547555 0.78 ALDH1A1 (0.46) ALDH1A1ALOX15ERN1G6PDCASP7
SCHEMBL29955463 0.78 ALDH1A1 (0.56) ALDH1A1ALOX15ERN1G6PDCASP7
SCHEMBL8580439 0.76 ALDH1A1 (0.50) ALDH1A1BCAT2KDM4EHPGDMAPT
SCHEMBL10651404 0.76 ALB (0.57) ALDH1A1ALOX15ERN1TSHRNR4A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108929438-A A kind of preparation method of polyamic acid and the method that polyimides is prepared by the polyamic acid 万华化学集团股份有限公司 2018-12-04 CN disclosed