Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 5/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3511705 | 0.81 | PARP1 (0.47) | ALDH1A1KDM4EHPGDMAPTTSHR | |
| SCHEMBL8578585 | 0.77 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDMAPTTSHR | |
| SCHEMBL8580566 | 0.76 | ERN1 (0.40) | ALDH1A1KDM4EHPGDMAPTTSHR | |
| SCHEMBL29951147 | 0.76 | KDM4E (0.57) | ALDH1A1KDM4EHPGDMAPTTSHR | |
| SCHEMBL28257533 | 0.76 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDMAPTTSHR | |
| SCHEMBL15210226 | 0.76 | ERN1 (0.44) | ALDH1A1KDM4EHPGDMAPTTSHR | |
| SCHEMBL4967588 | 0.75 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDMAPTTSHR | |
| SCHEMBL27700719 | 0.75 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDMAPTTSHR | |
| SCHEMBL39118 | 0.75 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDMAPTTSHR | |
| SCHEMBL8582279 | 0.75 | THRB (0.41) | ALDH1A1KDM4EHPGDMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792840-A | SUBSTITUTED GLUCOPYRANOSYL PHOSPHATES | SANKYO COMPANY, LIMITED (JP) | 1998-08-11 | — | — | US | disclosed |
| EP-0437016-B1 | Lipid A analogues having immunoactivating and anti-tumour activity | SANKYO CO (JP) | 1996-05-01 | — | — | EP | disclosed |
| EP-0437016-A2 | Lipid A analogues having immunoactivating and anti-tumour activity | Sankyo Company Limited (JP) | 1991-07-17 | — | — | EP | disclosed |