Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.55 |
| ▸ | CCND1 | P24385 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28255980 | 0.99 | CDK4 (0.57) | CDK4CCND1TDP1LMNAKMT2A | |
| SCHEMBL7873205 | 0.82 | CDK4 (0.60) | CDK4CCND1LMNAKMT2A | |
| SCHEMBL27624745 | 0.81 | KMT2A (0.57) | CDK4CCND1TDP1LMNAKMT2A | |
| SCHEMBL28866327 | 0.78 | BCL2 (0.44) | TDP1 | |
| SCHEMBL27452610 | 0.77 | CDK4 (0.59) | CDK4CCND1LMNAKMT2ADRD2 | |
| SCHEMBL29560163 | 0.75 | CDK4 (0.68) | CDK4CCND1LMNAKMT2ADRD2 | |
| SCHEMBL1967792 | 0.75 | CDK4 (0.68) | CDK4CCND1LMNAKMT2ADRD2 | |
| SCHEMBL1269116 | 0.74 | CDK4 (0.71) | CDK4CCND1LMNAKMT2ADRD2 | |
| SCHEMBL416566 | 0.74 | TDP1 (0.91) | TDP1LMNAKMT2A | |
| SCHEMBL223441 | 0.74 | TDP1 (1.00) | TDP1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108929259-A | A method of preparing Silodosin intermediate | 四川青木制药有限公司 | 2018-12-04 | — | — | CN | disclosed |