Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.46 |
| ▸ | CTSS | P25774 | 11/20 | 0.46 |
| ▸ | CTSL | P07711 | 3/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23822625 | 1.00 | CTSK (0.46) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL13955236 | 1.00 | CTSK (0.46) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL13936599 | 0.85 | CTSK (0.47) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL15369701 | 0.83 | CTSS (0.63) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL26206757 | 0.83 | CTSK (0.48) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL19560807 | 0.83 | CTSK (0.48) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL23805208 | 0.83 | GRN (0.41) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL23805209 | 0.83 | GRN (0.41) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL2569628 | 0.83 | CTSS (0.49) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL31276763 | 0.83 | PPARA (0.49) | CTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108794422-B | Heterocyclic compounds as PD-L1 inhibitors | 南京圣和药业股份有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-108863963-A | Heterocycle compound as PD-L1 inhibitor | 南京圣和药业股份有限公司 | 2018-11-23 | — | — | CN | disclosed |