Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK6 | P43250 | 1/20 | 0.71 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.41 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.41 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 8/20 | 0.37 |
| ▸ | GAA | P10253 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoquinone SCHEMBL28256504 | 0.84 | GRK6 (0.80) | GRK6MAPTGAAKMT2AKDM4E | |
| SCHEMBL29778809 | 0.84 | GRK6 (1.00) | GRK6MAPTGAAKMT2AKDM4E | |
| SCHEMBL8112 | 0.84 | GRK6 (1.00) | GRK6MAPTGAAKMT2AKDM4E | |
| Formaldehyde SCHEMBL27694578 | 0.82 | GRK6 (0.89) | GRK6MAPTGAAKMT2AKDM4E | |
| Bromide SCHEMBL31741343 | 0.82 | GRK6 (0.96) | GRK6SNCAMAPTGAAKMT2A | |
| Hydrochloric Acid SCHEMBL11423019 | 0.82 | GRK6 (0.96) | GRK6MAPTGAAKMT2AKDM4E | |
| Acetic Acid SCHEMBL15018560 | 0.77 | GRK6 (0.77) | GRK6MAPTGAAKMT2AKDM4E | |
| Phenanthroline SCHEMBL23829939 | 0.75 | GRK6 (0.73) | GRK6MAPTGAAKMT2AKDM4E | |
| Phenoxazine SCHEMBL27858947 | 0.73 | GRK6 (0.71) | GRK6MAPTGAAKMT2AKDM4E | |
| SCHEMBL27475210 | 0.73 | GRK6 (0.75) | GRK6MAPTGAAKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108947916-A | A kind of Perimidine naphthoquinone derivatives and its preparation method and application | 中山大学 | 2018-12-07 | — | — | CN | claimed |
| CN-108947916-A | A kind of Perimidine naphthoquinone derivatives and its preparation method and application | 中山大学 | 2018-12-07 | — | — | CN | disclosed |
| CN-108947916-A | A kind of Perimidine naphthoquinone derivatives and its preparation method and application | 中山大学 | 2018-12-07 | — | — | CN | disclosed |
| CN-108947916-A | A kind of Perimidine naphthoquinone derivatives and its preparation method and application | 中山大学 | 2018-12-07 | — | — | CN | disclosed |