Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 4/20 | 0.39 |
| ▸ | CDK2 | P24941 | 5/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PAK4 | O96013 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5867670 | 0.75 | CCNA2 (0.59) | CDK2CCNA2CCNA1 | |
| SCHEMBL19384989 | 0.75 | CTSL (0.52) | USP30 | |
| SCHEMBL5867954 | 0.73 | CCNA2 (0.54) | CDK2CCNA2CCNA1 | |
| SCHEMBL19385317 | 0.72 | USP30 (0.71) | KDM5AUSP30 | |
| SCHEMBL19385161 | 0.69 | CCNA2 (0.52) | CDK2CCNA2CCNA1 | |
| SCHEMBL5867446 | 0.69 | CCNA2 (0.51) | CDK2CCNA2CCNA1HDAC1LMNA | |
| SCHEMBL5867600 | 0.67 | CCNA2 (0.60) | CDK2CCNA2CCNA1 | |
| Methane SCHEMBL28241933 | 0.67 | KCNA3 (0.41) | OPRD1 | |
| SCHEMBL27625371 | 0.67 | DPP4 (0.36) | CYP3A4CHRM1KCNH2HTR1A | |
| SCHEMBL28017893 | 0.67 | ALDH1A1 (0.39) | CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884068-A | 1- cyano-pyrolidin derivative as DUB inhibitor | 特殊治疗有限公司 | 2018-11-23 | — | — | CN | disclosed |