Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 7/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 7/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | GRM8 | O00222 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28108227 | 0.80 | AKR1C3 (0.45) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL29009883 | 0.76 | AKR1C3 (0.49) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL24288624 | 0.75 | AKR1C3 (0.39) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL29009899 | 0.74 | AKR1C3 (0.43) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL1567845 | 0.73 | AKR1C3 (0.63) | MEN1CYP2C9CYP2C19KMT2AAKR1C3 | |
| SCHEMBL16464215 | 0.71 | TRPV3 (0.40) | EPHX1ARAKT1NR3C2 | |
| SCHEMBL8511925 | 0.71 | TRPV3 (0.40) | EPHX1ARAKT1NR3C2 | |
| SCHEMBL8511924 | 0.71 | TRPV3 (0.40) | EPHX1ARAKT1NR3C2 | |
| SCHEMBL14920365 | 0.71 | FFAR1 (0.41) | MEN1CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL27840751 | 0.71 | AKR1C3 (0.44) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106232579-B | As insecticide and acaricidal indole carboxamides and benzimidazole-carboxamide | 拜耳作物科学股份公司 | 2018-11-23 | — | — | CN | disclosed |