Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 10/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 10/20 | 0.49 |
| ▸ | KMO | O15229 | 2/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29009899 | 0.81 | AKR1C3 (0.43) | AKR1C3AKR1C2KMOAKR1C4AKR1C1 | |
| SCHEMBL7468152 | 0.80 | CES2 (0.49) | AKR1C3AKR1C2AKR1C4AKR1C1 | |
| SCHEMBL1567845 | 0.80 | AKR1C3 (0.63) | AKR1C3AKR1C2AKR1C4AKR1C1 | |
| SCHEMBL26508769 | 0.77 | IDO1 (0.40) | AKR1C3AKR1C2AKR1C4AKR1C1 | |
| SCHEMBL24288624 | 0.76 | AKR1C3 (0.39) | AKR1C3AKR1C2KMOAKR1C4AKR1C1 | |
| SCHEMBL28259237 | 0.76 | MEN1 (0.41) | AKR1C3AKR1C2KMOAKR1C4AKR1C1 | |
| SCHEMBL28382462 | 0.76 | CES2 (0.38) | AKR1C3AKR1C2AKR1C4AKR1C1 | |
| SCHEMBL15792073 | 0.75 | SLC6A4 (0.35) | KMOARSLC22A12SCN8A | |
| SCHEMBL27602817 | 0.75 | SLC6A4 (0.40) | AKR1C3AKR1C2ARSCN8A | |
| SCHEMBL17843617 | 0.75 | CES2 (0.53) | AKR1C3AKR1C2GRM4TTRTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116209433-A | Small molecule albumin binding agents | 俄勒冈健康科学大学 | 2023-06-02 | — | — | CN | disclosed |