Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.63 |
| ▸ | BCL9 | O00512 | 1/20 | 0.52 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9228347 | 0.90 | BCL9 (0.59) | MGLLBCL9CTNNB1FAAHTRPV1 | |
| SCHEMBL14907652 | 0.88 | MGLL (0.67) | MGLLBCL9CTNNB1FAAHTRPV1 | |
| SCHEMBL11980594 | 0.88 | MGLL (0.60) | MGLLBCL9CTNNB1FAAHTRPV1 | |
| SCHEMBL14907653 | 0.86 | MGLL (0.72) | MGLLBCL9CTNNB1FAAHTRPV1 | |
| SCHEMBL1389312 | 0.85 | MGLL (0.75) | MGLLBCL9CTNNB1FAAHTRPV1 | |
| SCHEMBL18359784 | 0.85 | MGLL (0.75) | MGLLBCL9CTNNB1FAAHTRPV1 | |
| SCHEMBL12651647 | 0.84 | MGLL (0.62) | MGLLBCL9CTNNB1FAAHTRPV1 | |
| SCHEMBL27356591 | 0.84 | MGLL (0.62) | MGLLBCL9CTNNB1FAAHTRPV1 | |
| SCHEMBL260968 | 0.84 | MGLL (0.68) | MGLLBCL9CTNNB1FAAHTRPV1 | |
| SCHEMBL30685129 | 0.83 | MGLL (0.60) | MGLLBCL9CTNNB1FAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108863963-A | Heterocycle compound as PD-L1 inhibitor | 南京圣和药业股份有限公司 | 2018-11-23 | — | — | CN | disclosed |