Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28257863 | 0.90 | MAPT (0.52) | ALOX12CYP1A2CYP3A4CYP2C19GAA | |
| SCHEMBL28257856 | 0.87 | ALDH1A1 (0.58) | GAALMNAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL28259537 | 0.87 | ALDH1A1 (0.56) | ALOX12CYP1A2CYP3A4CYP2C19GAA | |
| SCHEMBL28866500 | 0.87 | QPCT (0.49) | ALOX12CYP1A2CYP3A4CYP2C19GAA | |
| SCHEMBL28259439 | 0.87 | QPCT (0.49) | ALOX12CYP1A2CYP3A4CYP2C19GAA | |
| SCHEMBL28257859 | 0.86 | LMNA (0.49) | ALOX12CYP1A2CYP3A4CYP2C19GAA | |
| SCHEMBL28257850 | 0.85 | MAPT (0.51) | ALOX12CYP1A2CYP3A4CYP2C19GAA | |
| SCHEMBL28257855 | 0.85 | QPCT (0.48) | ALOX12CYP1A2CYP3A4CYP2C19GAA | |
| SCHEMBL28257858 | 0.84 | LMNA (0.61) | GAALMNAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL13805388 | 0.82 | QPCT (0.49) | ALOX12CYP1A2CYP3A4CYP2C19GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108863876-A | A kind of thiourea and preparation method and application with gibberellin function | 中国农业大学 | 2018-11-23 | — | — | CN | disclosed |