Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.55 |
| ▸ | ALPL | P05186 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28259453 | 0.88 | POLB (0.68) | LMNAPOLBMAPTGAAALDH1A1 | |
| SCHEMBL28259757 | 0.87 | LMNA (0.62) | LMNAPOLBMAPTGAAALDH1A1 | |
| SCHEMBL28259436 | 0.86 | LMNA (0.71) | LMNAPOLBMAPTGAAALDH1A1 | |
| SCHEMBL28257853 | 0.86 | LMNA (0.61) | LMNAPOLBMAPTGAAALDH1A1 | |
| SCHEMBL28411219 | 0.86 | CNR1 (0.69) | LMNAPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL28257889 | 0.86 | LMNA (0.61) | LMNAPOLBMAPTGAAALDH1A1 | |
| SCHEMBL28257851 | 0.84 | MAPT (0.61) | LMNAPOLBMAPTGAAALDH1A1 | |
| SCHEMBL28259650 | 0.84 | LMNA (0.58) | LMNAPOLBMAPTGAAALDH1A1 | |
| SCHEMBL28866630 | 0.83 | RAB9A (0.72) | LMNAPOLBMAPTGAAALDH1A1 | |
| SCHEMBL28259445 | 0.83 | LMNA (0.64) | LMNAPOLBMAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108863876-A | A kind of thiourea and preparation method and application with gibberellin function | 中国农业大学 | 2018-11-23 | — | — | CN | disclosed |