SCHEMBL28259656

SCHEMBL28259656

CCCCOc1cccc(C(Cl)Cl)c1

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.51
LTA4H P09960 2/20 0.50
KDM4E B2RXH2 1/20 0.50
KMT2A Q03164 1/20 0.50
CACNA1B Q00975 1/20 0.49
CYSLTR2 Q9NS75 3/20 0.49
CYSLTR1 Q9Y271 3/20 0.49
ALOX5 P09917 2/20 0.48
PTGES O14684 1/20 0.47
PPARG P37231 1/20 0.47
PPARA Q07869 1/20 0.47
TLR4 O00206 1/20 0.47
TLR2 O60603 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP19A1 P11511 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12652785 0.86 KDM4E (0.67) TSHRLTA4HKDM4EKMT2ACACNA1B
SCHEMBL14347947 0.84 ALOX5 (0.53) TSHRLTA4HKDM4ECACNA1BCYSLTR2
SCHEMBL25080975 0.84 CACNA1B (0.54) TSHRLTA4HKDM4ECACNA1BCYSLTR2
SCHEMBL14066695 0.83 CACNA1B (0.53) TSHRLTA4HKDM4ECACNA1BCYSLTR2
SCHEMBL16950919 0.83 TSHR (0.51) TSHRLTA4HKDM4ECACNA1BCYSLTR2
SCHEMBL14119424 0.83 TSHR (0.51) TSHRLTA4HKDM4ECACNA1BCYSLTR2
SCHEMBL26696139 0.83 TSHR (0.53) TSHRLTA4HKDM4ECACNA1BCYSLTR2
SCHEMBL4397448 0.82 TSHR (0.63) TSHRLTA4HKMT2ACYSLTR2CYSLTR1
SCHEMBL11293403 0.81 LTA4H (0.54) TSHRLTA4HKDM4ECACNA1BCYSLTR2
Hydrochloric Acid SCHEMBL28661273 0.81 TSHR (0.51) TSHRLTA4HKDM4ECACNA1BCYSLTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109111463-A The manufacturing method of aromatic compound DIC株式会社 2019-01-01 CN disclosed