Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24775175 | 0.92 | SMN1; SMN2 (0.49) | HTR2AHTR2CHTR2BHCRTR2MAPT | |
| SCHEMBL24775070 | 0.92 | SMN1; SMN2 (0.49) | HTR2AHTR2CHTR2BHCRTR2MAPT | |
| SCHEMBL24774754 | 0.81 | HTR2C (0.47) | HTR2CHTR2BHCRTR2HCRTR1SMN1; SMN2 | |
| SCHEMBL24774522 | 0.77 | HTR2A (0.39) | HTR2AHCRTR2HCRTR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL24774523 | 0.75 | HSP90AA1 (0.36) | SMN1; SMN2ALDH1A1LMNAKDM4E | |
| SCHEMBL24775062 | 0.75 | HTR1B (0.45) | SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL24775174 | 0.75 | HSP90AA1 (0.47) | HTR2CALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL24775072 | 0.75 | HSP90AA1 (0.47) | HTR2CALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL23323111 | 0.75 | SMN1; SMN2 (0.52) | HTR2AHTR2CHTR2BHCRTR2HCRTR1 | |
| SCHEMBL24775443 | 0.74 | RIPK1 (0.35) | HTR2CSSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109010343-A | The purposes of Pyrazolopyrimidine derivative treatment PI3K δ associated disease | 因赛特公司 | 2018-12-18 | — | — | CN | disclosed |