SCHEMBL28260433

SCHEMBL28260433

Oc1cc(Cl)cc(Oc2cccc(Cl)c2Cl)c1F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RHEB Q15382 3/20 0.41
SLC6A2 P23975 2/20 0.41
SLC6A3 Q01959 2/20 0.41
HTR1A P08908 1/20 0.41
SLC6A4 P31645 1/20 0.41
HPGD P15428 3/20 0.40
TTR P02766 3/20 0.40
TSHR P16473 3/20 0.40
HSP90AA1 P07900 2/20 0.40
MAPT P10636 2/20 0.40
NR1I2 O75469 1/20 0.40
LMNA P02545 1/20 0.40
PGR P06401 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
HSPA5 P11021 1/20 0.40
CBR1 P16152 1/20 0.40
TBXA2R P21731 1/20 0.40
AGTR1 P30556 1/20 0.40
ALDH1A1 P00352 3/20 0.38
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2136172 0.79 TTR (0.66) RHEBSLC6A2SLC6A3HPGDTTR
SCHEMBL28053158 0.76 SLC6A2 (0.45) RHEBSLC6A2SLC6A3HTR1ASLC6A4
SCHEMBL28061476 0.76 TSHR (0.64) RHEBSLC6A2SLC6A3HTR1ASLC6A4
SCHEMBL28258898 0.76 MEN1 (0.49) RHEBSLC6A2SLC6A3HTR1ASLC6A4
SCHEMBL6325195 0.75 RHEB (0.60) RHEBSLC6A2SLC6A3HTR1ASLC6A4
SCHEMBL663381 0.74 TSHR (0.56) RHEBSLC6A2SLC6A3HTR1ASLC6A4
SCHEMBL10930169 0.72 RHEB (0.50) RHEBSLC6A2SLC6A3HTR1ASLC6A4
Alcohol SCHEMBL28760937 0.70 TSHR (0.55) RHEBSLC6A2SLC6A3HTR1ASLC6A4
SCHEMBL2855174 0.70 TTR (0.49) RHEBSLC6A2SLC6A3HPGDTTR
SCHEMBL2862316 0.69 TSHR (0.54) RHEBSLC6A2SLC6A3HTR1ASLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105669576-B A kind of Fungicidal compounds, microbicide compositions and preparation and its application 浙江博仕达作物科技有限公司 2018-12-04 CN disclosed