SCHEMBL28053158

SCHEMBL28053158

Oc1cc(Cl)c(Oc2cccc(Cl)c2Cl)cc1F

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.45
SLC6A3 Q01959 2/20 0.45
HTR1A P08908 1/20 0.45
SLC6A4 P31645 1/20 0.45
TTR P02766 4/20 0.42
HSP90AA1 P07900 2/20 0.42
MAPT P10636 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
RHEB Q15382 1/20 0.42
TSHR P16473 1/20 0.41
HPGD P15428 2/20 0.41
NR1I2 O75469 1/20 0.41
LMNA P02545 1/20 0.41
PGR P06401 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
HSPA5 P11021 1/20 0.41
CBR1 P16152 1/20 0.41
TBXA2R P21731 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15094293 0.79 TSHR (0.47) SLC6A2SLC6A3HTR1ASLC6A4TTR
SCHEMBL28061476 0.77 TSHR (0.64) SLC6A2SLC6A3HTR1ASLC6A4TTR
SCHEMBL2136172 0.77 TTR (0.66) SLC6A2SLC6A3TTRHSP90AA1MAPT
SCHEMBL6325195 0.76 RHEB (0.60) SLC6A2SLC6A3HTR1ASLC6A4TTR
SCHEMBL28260433 0.76 RHEB (0.41) SLC6A2SLC6A3HTR1ASLC6A4TTR
SCHEMBL663381 0.75 TSHR (0.56) SLC6A2SLC6A3HTR1ASLC6A4TTR
SCHEMBL28053101 0.75 MEN1 (0.50) SLC6A2SLC6A3HTR1ASLC6A4TTR
SCHEMBL10930169 0.73 RHEB (0.50) SLC6A2SLC6A3HTR1ASLC6A4TTR
SCHEMBL8515928 0.73 RHEB (0.46) SLC6A2SLC6A3HTR1ASLC6A4TTR
Alcohol SCHEMBL28760937 0.71 TSHR (0.55) SLC6A2SLC6A3HTR1ASLC6A4TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105669576-A Germicidal compound, germicide composition and preparation and application of germicide composition and preparation 华中师范大学 2016-06-15 CN disclosed