SCHEMBL6325195

SCHEMBL6325195

Clc1cccc(Oc2cccc(Cl)c2Cl)c1Cl

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RHEB Q15382 1/20 0.60
ALDH1A1 P00352 2/20 0.55
HTR1A P08908 2/20 0.49
SLC6A2 P23975 2/20 0.49
SLC6A4 P31645 2/20 0.49
SLC6A3 Q01959 2/20 0.49
TSHR P16473 2/20 0.46
MEN1 O00255 1/20 0.45
TTR P02766 1/20 0.45
HSP90AA1 P07900 1/20 0.45
MAPT P10636 1/20 0.45
KMT2A Q03164 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
CYP1A2 P05177 2/20 0.43
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C19 P33261 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28061476 0.87 TSHR (0.64) RHEBALDH1A1HTR1ASLC6A2SLC6A4
SCHEMBL10930169 0.87 RHEB (0.50) RHEBALDH1A1HTR1ASLC6A2SLC6A4
SCHEMBL11432978 0.85 AR (0.50) RHEBALDH1A1HTR1ASLC6A2SLC6A4
SCHEMBL663381 0.85 TSHR (0.56) RHEBALDH1A1HTR1ASLC6A2SLC6A4
SCHEMBL6851318 0.84 ALDH1A1 (0.47) RHEBALDH1A1HTR1ASLC6A2SLC6A4
SCHEMBL3667279 0.84 DPP4 (0.61) RHEBALDH1A1TSHRMEN1TTR
SCHEMBL11766505 0.83 PNMT (0.48) RHEBALDH1A1HTR1ASLC6A2SLC6A4
SCHEMBL8128469 0.82 CYP2A6 (0.52) RHEBALDH1A1HTR1ASLC6A2SLC6A4
SCHEMBL8124193 0.82 RHEB (0.46) RHEBALDH1A1HTR1ASLC6A2SLC6A4
SCHEMBL8515928 0.82 RHEB (0.46) RHEBALDH1A1HTR1ASLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1195002-C Polyaryl thioether sulfone and its preparation method UNIV SICHUAN (CN) 2005-03-30 CN claimed
CN-1461763-A Polyaryl thioether sulfone and its preparation method UNIV SICHUAN (CN) 2003-12-17 CN claimed
CN-221971370-U Sewage treatment hydrolysis acidification pool 绩溪县现代化工有限责任公司 2024-11-08 CN disclosed
WO-2024146005-A1 ISOBUTYLENE POLYMERIZATION INITIATION SYSTEM COMPOSITION, POLYMERIZATION METHOD AND USE 浙江信汇新材料股份有限公司 2024-07-11 WO disclosed
WO-2024053579-A1 PHOTOSENSITIVE RESIN COMPOSITION 東京応化工業株式会社 2024-03-14 WO disclosed
CN-116162188-B Isobutene polymerization initiation system composition, polymerization method and application 浙江信汇新材料股份有限公司 2024-01-26 CN disclosed
CN-114727605-B Mixture of encapsulated phenothrin and emulsified dexprallethrin 杰斯蒙德控股公司 2023-08-18 CN disclosed
CN-116297918-A High-throughput screening detection method for pesticide residues in plant extracts 西安海关技术中心 2023-06-23 CN disclosed
CN-116162188-A Isobutene polymerization initiation system composition, polymerization method and application 浙江信汇新材料股份有限公司 2023-05-26 CN disclosed
CN-111788252-B Polyether sulfone-ether imide copolymer and preparation method thereof 广东优巨先进新材料股份有限公司 2023-04-28 CN disclosed
CN-115725010-A Preparation method of polyisobutylene with medium and high molecular weights, initiation system and application thereof 浙江信汇新材料股份有限公司 2023-03-03 CN disclosed
CN-1195002-C Polyaryl thioether sulfone and its preparation method UNIV SICHUAN (CN) 2005-03-30 CN disclosed
US-20040127726-A1 Method for purifying an organic solvent for the purposes of absorption of maleic acid anhydride BASF AKTIENGESELLSCHAFT (DE) 2004-07-01 US disclosed
CN-1503773-A Method for purifying organic solvent for absorbing maleic anhydride �����ɷ� 2004-06-09 CN disclosed
CN-1461763-A Polyaryl thioether sulfone and its preparation method UNIV SICHUAN (CN) 2003-12-17 CN disclosed
US-5767171-A A MARINE, HYDROLYZABLE, ANTIFOULING, PROTECTIVE COATING BASED ON A POLYMER OF A TRIALKYLSILYL (METH)ACRYLATE AND AN ALKYLOXYALKYL (METH)ACRYLATE; NONCRACKING; UNIFORM EROSION; ADHESION NOF CORPORATION (JP) 1998-06-16 US disclosed
CN-1172585-A Pesticide for killing corn borer UNIV SHENYANG AGRICULTURAL (CN) 1998-02-11 CN disclosed
US-4355960-A OIL ADDITIVE WESTINGHOUSE ELECTRIC CORP. (US) 1982-10-26 US disclosed
US-3981888-A Process for preparing (1-oxo-2-phenyl, halophenyl or thienyl-2-methyl-6,7-dichloro-5-indanyloxy)acetic acid MERCK & CO., INC. (US) 1976-09-21 US disclosed
US-3950408-A Process for preparing [1-oxo-2-cyclopentyl (or 2-isopropyl)-2-methyl-6,7-dichloro-5-indanyloxy] acetic acid MERCK & CO., INC. (US) 1976-04-13 US disclosed