Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SDCBP | O00560 | 1/20 | 0.33 |
| ▸ | SDC2 | P34741 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28260461 | 0.86 | SMN1; SMN2 (0.48) | SMN1; SMN2SRD5A1TSHRCA1CA2 | |
| SCHEMBL28351995 | 0.85 | SMN1; SMN2 (0.66) | SMN1; SMN2PRNPCA1CA2CA4 | |
| SCHEMBL28355728 | 0.82 | HTR2A (0.43) | SMN1; SMN2TSHRALDH1A1KDM4EMAPT | |
| SCHEMBL28352234 | 0.80 | BACE1 (0.36) | SMN1; SMN2PARP10TDP2CA1CA2 | |
| SCHEMBL28260480 | 0.80 | SMN1; SMN2 (0.43) | SMN1; SMN2CA1CA2CA7CA9 | |
| SCHEMBL30484524 | 0.79 | SMN1; SMN2 (0.44) | SMN1; SMN2SRD5A1SRD5A2PARP10PARP11 | |
| SCHEMBL30484570 | 0.79 | SMN1; SMN2 (0.44) | SMN1; SMN2SRD5A1SRD5A2PARP10PARP11 | |
| SCHEMBL28261809 | 0.79 | TSHR (0.41) | SMN1; SMN2SRD5A1PARP10TSHRCA1 | |
| SCHEMBL28260511 | 0.79 | SMN1; SMN2 (0.40) | SMN1; SMN2SRD5A1SRD5A2PARP10TSHR | |
| SCHEMBL28351697 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2CA1CA2CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108997183-B | Difluoromethylation reagent and preparation method and application thereof | 深圳大学 | 2020-02-07 | — | — | CN | claimed |
| CN-108997183-A | A kind of difluoromethyl reagent and the preparation method and application thereof | 深圳大学 | 2018-12-14 | — | — | CN | disclosed |