Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28351697 | 0.90 | SMN1; SMN2 (0.53) | SMN1; SMN2KDM4EMAPTALDH1A1MAPK14 | |
| SCHEMBL28260461 | 0.86 | SMN1; SMN2 (0.48) | SMN1; SMN2MAPK14CA1CA2CA7 | |
| SCHEMBL28260554 | 0.85 | SMN1; SMN2 (0.47) | SMN1; SMN2PRNPKDM4EMAPTALDH1A1 | |
| SCHEMBL28260480 | 0.82 | SMN1; SMN2 (0.43) | SMN1; SMN2KDM4EMAPTGAAATM | |
| SCHEMBL28355728 | 0.82 | HTR2A (0.43) | SMN1; SMN2KDM4EMAPTGAAATM | |
| SCHEMBL28356027 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2KDM4EGAAALDH1A1MAPK14 | |
| SCHEMBL28261809 | 0.79 | TSHR (0.41) | SMN1; SMN2MAPK14CA1CA2CA7 | |
| SCHEMBL28260511 | 0.79 | SMN1; SMN2 (0.40) | SMN1; SMN2GAAALDH1A1DGAT1 | |
| SCHEMBL13477088 | 0.79 | SMN1; SMN2 (0.70) | SMN1; SMN2PRNPKDM4EGLAMAPT | |
| SCHEMBL13477053 | 0.79 | SMN1; SMN2 (0.70) | SMN1; SMN2PRNPKDM4EGLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108997183-B | Difluoromethylation reagent and preparation method and application thereof | 深圳大学 | 2020-02-07 | — | — | CN | claimed |