Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.69 |
| ▸ | HTT | P42858 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | FABP3 | P05413 | 1/20 | 0.55 |
| ▸ | FABP4 | P15090 | 1/20 | 0.55 |
| ▸ | PRNP | P04156 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.55 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TACR1 | P25103 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27658279 | 0.87 | GAA (0.77) | NPSR1MAPTGAASMN1; SMN2HTT | |
| SCHEMBL2822088 | 0.86 | MAPT (0.75) | NPSR1MAPTGAASMN1; SMN2HTT | |
| SCHEMBL30079692 | 0.86 | MAPT (0.75) | NPSR1MAPTGAASMN1; SMN2HTT | |
| SCHEMBL2821515 | 0.83 | RXFP1 (0.81) | NPSR1MAPTGAASMN1; SMN2HTT | |
| SCHEMBL28879006 | 0.81 | MAPT (0.68) | NPSR1MAPTGAASMN1; SMN2HTT | |
| SCHEMBL28958192 | 0.81 | MAPT (0.68) | NPSR1MAPTGAASMN1; SMN2HTT | |
| SCHEMBL2821858 | 0.81 | MAPT (0.68) | NPSR1MAPTGAASMN1; SMN2HTT | |
| SCHEMBL2821517 | 0.80 | NPSR1 (0.67) | NPSR1MAPTGAASMN1; SMN2HTT | |
| SCHEMBL5505353 | 0.80 | SMN1; SMN2 (0.97) | NPSR1MAPTGAASMN1; SMN2HTT | |
| SCHEMBL31442528 | 0.80 | SMN1; SMN2 (0.97) | NPSR1MAPTGAASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809605-B1 | QUINOLINES AS ALLOSTERIC ENHANCERS OF THE GABA-B RECEPTORS | HOFFMANN LA ROCHE (CH) | 2010-08-11 | — | — | EP | claimed |
| CN-114249689-A | Synthetic method of benzoyl quinoline compound | 温州大学 | 2022-03-29 | — | — | CN | disclosed |