Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ACACA | Q13085 | 2/20 | 0.45 |
| ▸ | FABP3 | P05413 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12781497 | 0.86 | MAPT (0.54) | MAPTNPSR1GAASMN1; SMN2LMNA | |
| SCHEMBL2826091 | 0.81 | NPSR1 (1.00) | MAPTNPSR1GAASMN1; SMN2LMNA | |
| SCHEMBL28958192 | 0.81 | MAPT (0.68) | MAPTNPSR1GAASMN1; SMN2LMNA | |
| SCHEMBL28878936 | 0.78 | GAA (0.63) | MAPTNPSR1GAASMN1; SMN2LMNA | |
| SCHEMBL14463535 | 0.77 | SMN1; SMN2 (0.74) | MAPTNPSR1GAASMN1; SMN2LMNA | |
| SCHEMBL13531355 | 0.76 | KMT2A (0.55) | MAPTNPSR1GAASMN1; SMN2LMNA | |
| SCHEMBL18456032 | 0.76 | KDM4E (0.53) | MAPTNPSR1GAASMN1; SMN2LMNA | |
| SCHEMBL14463978 | 0.76 | SMN1; SMN2 (0.60) | MAPTNPSR1GAASMN1; SMN2LMNA | |
| SCHEMBL8776502 | 0.74 | HTT (0.61) | MAPTNPSR1GAASMN1; SMN2LMNA | |
| SCHEMBL27618204 | 0.74 | NPSR1 (0.58) | MAPTNPSR1GAASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114249689-A | Synthetic method of benzoyl quinoline compound | 温州大学 | 2022-03-29 | — | — | CN | disclosed |